Ayurveda, the science of life, evolved as a comprehensive system of healthcare systematically through scientific experimentations of high order backed by sound and reproducible evidence base and stood the test of the time. Several strategies and road maps are being drawn to carry forward merits of this science so as to meet the current day health needs and mainstream its core strengths alongside through research & development in this country and across the globe. The core component of pharmacology research comprise of validation of the Ayurvedic formulations medicinal plants by different biological screening methods and safety/toxicity studies, find out effective dose range and dose dependent effect and generation biological screening data for clinical implementation, contemporary scientific and pharmacological leads for important diseases of National importance based on strength of Ayurveda and from the folklore collected from various parts of India by the Council.